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. 2023 Nov 30;23:264. doi: 10.1186/s12902-023-01467-3

Table 3.

The association of opium consumption with different level of thyroid related hormones

Group Non-user User Chi-square
P value*
crude model
OR (95%CI) **
Adjusted model
OR (95%CI) ***
low-TSH 30 8 0.012 0.69 (0.31, 1.55) 0.67 (0.26, 1.71)
Normal-TSH 427 164 1 (ref) 1 (ref)
High-TSH 30 25 2.17 (1.24, 3.80) 3.21 (1.66, 6.22)
low_T4 0 55 < 0.001 ERROR ERROR
Normal_T4 431 130 1 (ref) 1 (ref)
high_T4 56 12 0.71 (0.37, 1.37) 0.74 (0.33, 1.68)
low_T3 0 38 < 0.001 ERROR ERROR
Normal_T3 436 146 1 (ref) 1 (ref)
high_T3 51 13 0.76 (0.40, 1.44) 0.71 (0.31, 1.60)

* The significant difference of thyroid related hormones between users and non-users was considered P-value < 0.05 (Chi-square)

** The crude model was performed adjusted for no covariates

*** The adjusted model was performed adjusted for gender + age + body mass index + educational status + smoking + alcohol consumption + diabetes + myocardial infarction + cardiac disease + hypertension + fatty liver disease