Table 5. Hormonal date in according to thyroid morphology in 58 children with permanent (PCH) and 30 with transient (TCH) congenital hypothyroidism.
| Gland in situ | Hyperplasia | Dysgenesis | P | ||
|---|---|---|---|---|---|
| N | 77 | 5 | 6 | ||
| Bloodspot TSH (µU/mL) | 7.5 (5.2) | 101.4 (87.0) | 162.7 (265.5) | <0.0001 | |
| Initial serum TSH (µU/mL) | 8.7 (16.4) | 223.0 (415.1) | 333.0 (594.6) | 0.001 | |
| Initial serum fT4 (ng/dL) | 1.0 (0.3) | 0.4 (0.7) | 0.8 (0.12) | 0.039 | |
Values expressed as median (interquartile range) and compared by the Kruskal-Wallis's test. The pairwise comparisons showed for neonatal blood spot TSH that gland in situ x hyperplasia: p = 0.045, situ x dysgenesis: p = 0.001. For serum initial TSH, gland in situ x dysgenesis: p = 0.005.