Table 3.
ARHGAP11B expression in TCGA cancers.
Cancer type | Fold change | log2 (fold change) | Mean TPM (tumor) | Mean TPM (normal) | P value | Adjusted P value |
---|---|---|---|---|---|---|
Breast invasive carcinoma | 4.69 | 2.23 | 480.03 | 102.32 | 3.77e‐50 | 7.52e‐49 |
Pan-kidney cohort (KICH+KIRC+KIRP) | 2.95 | 1.56 | 135.41 | 45.88 | 1.36e‐47 | 2.28e‐46 |
Lung squamous cell carcinoma | 8.44 | 3.08 | 766.07 | 90.72 | 1.96e‐31 | 1.3e‐29 |
Kidney renal clear cell carcinoma | 2.74 | 1.45 | 160.72 | 58.66 | 1.78e‐30 | 1.49e‐29 |
Lung adenocarcinoma | 4.35 | 2.12 | 394.06 | 90.63 | 1.77e‐27 | 2.56e‐26 |
Stomach and esophageal carcinoma | 4.08 | 2.03 | 1000.62 | 245.54 | 1.53e‐23 | 4.71e‐21 |
Liver hepatocellular carcinoma | 6.27 | 2.65 | 235.47 | 37.56 | 1.91e‐23 | 7.06e‐22 |
Uterine corpus endometrial carcinoma | 6.59 | 2.72 | 511.13 | 77.58 | 2.15e‐20 | 8.37e‐19 |
Stomach adenocarcinoma | 3.78 | 1.92 | 922.81 | 244.37 | 2.99e‐17 | 5.44e‐15 |
Head and neck squamous cell carcinoma | 2.24 | 1.16 | 760.27 | 339.19 | 1.39e‐14 | 2.1e‐13 |
Kidney renal papillary cell carcinoma | 2.7 | 1.43 | 84.99 | 31.48 | 1.21e‐12 | 8.74e‐12 |
Colon adenocarcinoma | 1.89 | 0.92 | 770.75 | 406.89 | 8.73e‐11 | 2.47e‐10 |
Kidney chromophobe | 5.51 | 2.46 | 160.32 | 29.09 | 1.58e‐10 | 1.34e‐9 |
Bladder urothelial carcinoma | 2.55 | 1.35 | 579.21 | 227.08 | 2.56e‐8 | 3.52e‐7 |
Esophageal carcinoma | 4.71 | 2.23 | 1174.79 | 249.58 | 2.92e‐7 | 2.7e‐05 |
Prostate adenocarcinoma | 1.64 | 0.71 | 95.69 | 58.33 | 3.5e‐7 | 1.1e‐06 |
Cholangiocarcinoma | 4.78 | 2.26 | 273.22 | 57.11 | 1e‐05 | 5.3e‐05 |
Cervical squamous cell carcinoma and endocervical adenocarcinoma | 29.52 | 4.88 | 936.65 | 31.73 | 0.0029 | 0.0418 |
Thyroid carcinoma | 1.14 | 0.19 | 84.17 | 73.93 | 0.0035 | 0.00518 |
Rectum adenocarcinoma | 1.47 | 0.56 | 722.45 | 491.06 | 0.0352 | 0.0595 |
TMP: Transcript per million.