Table 1. Movement disorders associated to hereditary spastic paraplegia (SPG).
| Movement disorder | HSP | Gene | Inheritance |
|---|---|---|---|
| Ataxia | SPG4 | SPAST | AD |
| SPG6 | NIPA1 | AD | |
| SPG7 | SPG7 | AD | |
| SPG10 | KIF5A | AD | |
| SPG11 | KIAA1840 | AR | |
| SPG27 | 10q22.1-q24.1 | AR | |
| SPG30 | KIF1A | AR | |
| SPG31 | REEP1 | AD | |
| Dystonia | SPG7 | SPG7 | AD |
| SPG11 | SPG11 | AR | |
| SPG22 | SLC16A2 | XLR | |
| SPG26 | B4GALNT1 | AR | |
| SPG35 | FA2H | AR | |
| SPG48 | AP5Z1 | AR | |
| SPG49 | TECPR2 | AR | |
| SPG58 | KIF1C | AR | |
| SPG64 | ENTPD1 | AR | |
| SPG76 | CAPN1 | AR | |
| Myoclonus | SPG4 | SPAST | AD |
| SPG7 | SPG7 | AD | |
| SPG35 | FA2H | AR | |
| SPG48 | AP5Z1 | AR | |
| Parkinsonism | SPG7 | SPG7 | AD |
| SPG4 | SPAST | AD | |
| SPG11 | KIAA1840 | AR | |
| SPG15 | ZFYVE26 | AR | |
| SPG48 | AP5Z1 | AR | |
| Tremor | SPG7 | SPG7 | AD |
| SPG9 | ALDH18A1 | AR | |
| SPG11 | SPG11 | AR | |
| SPG15 | ZFYVE26 | AR | |
| SPG76 | CAPN1 | AR |
Abbreviations: AD, Autossomal dominant; AR, Autossomal recessive; XLR, X-linked recessive.