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. 2023 Jun 5;16(12):2405–2416. doi: 10.1093/ckj/sfad132

Table 1:

The clinical and pathological characteristics of CR patients.

CR patients
Characteristics/number 1 2 3 4 5 6 7 8 9
Age at diagnosis, years 60 58 56 74 52 65 59 74 67
Gender M M F F M M M M M
Course of disease, years 5 4 4 4 3 4 2 2 2
BMI at diagnosis, kg/m2 24.6 26.3 24.8 27.5 25.1 22.2 26 24.5 23.7
BP at diagnosis, mmHg 160/106 150/80 118/90 133/77 120/70 165/90 156/82 150/81 140/82
eGFR at diagnosis, mL/min/1.73 m2 (CKD-EPI) 89.2 61.3 101.3 74.8 102.8 58.7 63.7 58.2 61.9
Creatinine at diagnosis, µmol/L 82 113 54 69 75 112 109 108 107
24 h UTP at diagnosis, g/day 11.2 7.54 4.99 7.48 3.68 9.85 8.84 9.2 4.34
Albumin at diagnosis, g/L 14.1 32.1 20.5 25.3 23.2 16 17.2 15 22.9
Serum PLA2R at diagnosis, RU/mL ND 24.37 62.09 0.87 ND 49.29 427.98 53.43 34.07
Complication Hypertension Hypertension/diabetes No Hypertension No Hypertension Hypertension Hypertension Gout
Immunosuppressor CTX Tacrolimus/CTX CTX/rituximab Tacrolimus CTX CTX/Tacrolimus Tacrolimus Rituximab CTX
MN class I I–II I II I I I II II
IF IgG 3+ 3+ 3+ 3+ 3+ 3+ 3+ 3+ 3+
IF IgA Neg Neg Neg Neg Neg Neg Neg Neg Neg
IF C3 3+ 2+ 1+ 2+ Neg 2+ 2+ 2+ 3+
IF C1q Neg Neg Neg Neg Neg Neg Neg Neg Neg
Tissue PLA2R Neg Pos Pos Pos Pos Pos Pos Pos Pos
Global sclerosis (%) 10 9 0 6 4 0 6 0 0
Segmental sclerosis 0/10 0/32 0/3 0/20 0/28 1/6 0/17 0/21 0/16
Crescent 0/10 0/32 0/3 0/20 0/28 0/6 0/17 0/21 0/16
Interstitial fibrosis (%) 5 5 0 10 0 15 10 10 5
Mesangial matrix increase Neg Mild Neg Neg Mild Neg Neg Mild neg
Interstitial lymphocytes Neg Neg Mild Mild Neg Mild Mild Mild Mild
Arterial sclerosis Mild Mild Mild Mild Mild Neg Mild Mild Neg

M: male; F: female; BMI: body mass index BP: blood pressure; UTP: urine total protein; CTX: cyclophosphamide; Neg: negative; Pos: positive.