Table 2.
Response Rate
| Variable | BMRR Is Assessed by PAREXEL Criteria | BMRR Is Assessed by RECIST Criteria | ORR Is Assessed by RECIST Criteria |
|---|---|---|---|
| n | 26 | 13 | 25 |
| Response, n (%) | |||
| CR | 5 (19.2) | 1 (7.7) | 0 (0) |
| PR | 15 (57.7) | 9 (69.2) | 16 (64.0) |
| SD | 3 (11.5) | 1 (7.7) | 5 (20.0) |
| PD | 1 (3.8) | 1 (7.7) | 0 (0) |
| NE | 2 (7.7) | 1 (7.7) | 4 (16.0) |
| Response rate | 76.9% | 76.9% | 64.0% |
| 90% CI | 63.3%–90.5% | ||
| 95% CI | 54.0%–99.8% | 45.2%–82.8% |
BMRR, brain metastasis response rate; CI, confidence interval; CR, complete response; NE, not evaluable; ORR, overall response rate; PD, progressive disease; PR, partial response; RECIST, Response Evaluation Criteria in Solid Tumors; SD, stable disease.