Table 3.

Summary of TEAEs related to study medication

	Trifarotene N = 121 n (%) [events]		Vehicle N = 121 n (%) [events]	Overall N = 121 n (%) [events]
Subjects with any TEAE related to study drug	6 (5.0) [8]		2 (1.7) [2]	9 (7.4) [12]
General disorders and administration site conditions	4 (3.3) [5]		2 (1.7) [2]	6 (5.0) [8]
Pruritus	1 (0.8) [1]		1 (0.8) [1]	2 (1.7) [2]
Skin tightness	2 (1.7) [2]		1 (0.8) [1]	2 (1.7) [3]
Dermatitis contact	0		0	1 (0.8) [1]
Erythema	1 (0.8) [1]		0	1 (0.8) [1]
Rash	1 (0.8) [1]		0	1 (0.8) [1]
General disorders and administration site conditions	2 (1.7) [2]		0	2 (1.7) [2]
Adverse reaction	1 (0.8) [1]		0	1 (0.8) [1]
Face edema	1 (0.8) [1]		0	1 (0.8) [1]
Injury, poisoning and procedural complications	0		0	1 (0.8) [1]
Accidental exposure to product	0		0	1 (0.8) [1]
Nervous system disorders	1 (0.8) [1]		0	1 (0.8) [1]
Burning sensation	1 (0.8) [1]		0	1 (0.8) [1]