Skip to main content
. 2023 Sep 21;5(4):538–550. doi: 10.1007/s42995-023-00185-y

Table 2.

Mutation rates of the wild-type, lexA3, ΔmutS and ΔmutY MA lines

Strain Group BPSs MR Confidence intervals Indels MR Confidence intervals
Wild-type WA 2.08 1.56 2.72 2.36 0.87 5.13
1.06 0.29 2.72 5.31 0.64 19.2
Wild-type WB 2.33 1.8 2.98 2.55 1.03 5.26
2.22 1.01 4.21 2.46 0.06 13.7
Wild-type WC 3.96 3.22 4.82 6.34 3.62 10.3
3.47 1.85 5.93 5.34 0.65 19.3
Wild-type WD 5.26 4.35 6.30 12.9 8.65 18.6
4.80 2.74 7.79 12.0 3.27 30.7
Wild-type WE 6.29 5.31 7.39 11.5 7.56 16.7
6.28 3.94 9.51 8.56 1.77 25.0
lexA3 LA 1.58 1.14 2.14 0.75 0.09 2.72
0.762 0.157 2.23 0 0 9.37
lexA3 LB 1.91 1.44 2.48 3.75 1.87 6.71
1.38 0.507 3.01 2.30 0.06 12.8
lexA3 LC 1.96 1.47 2.56 4.43 2.29 7.74
1.49 0.548 3.25 2.49 0.06 13.9
lexA3 LD 2.92 2.23 3.76 3.90 1.68 7.67
1.64 0.533 3.83 0 0 12.1
lexA3 LE 4.31 3.41 5.37 6.00 2.99 10.7
3.31 1.51 6.27 3.67 0.09 20.5
ΔmutS SA 232 218 247 440 379 509
ΔmutS SB 268 252 284 426 365 494
ΔmutS SC 290 274 308 541 470 620
ΔmutS SD 287 275 299 393 351 438
ΔmutS SE 334 316 353 649 571 735
ΔmutY YA 16.9 14.8 19.2 4.34 1.59 9.45
ΔmutY YC 18.1 16.2 20.3 2.87 0.93 6.70
ΔmutY YD 25.4 22.9 28.1 6.75 3.24 12.4
ΔmutY YE 24.5 22.1 27.2 6.02 2.75 11.4
ΔmutY YF 23.2 20.8 25.9 21.1 14.3 30.2

Mutation rates are in units of per nucleotide site per cell division. Bolded areas show information at four-fold degenerate sites. BPSs MR, base-substitution mutation rate (× 10–10); Indels MR, small indels mutation rate (× 10–11); confidence intervals are 95% Poisson confidence intervals (applying to tables below too) for BPSs MR (× 10–10) and Indels MR (× 10–11) respectively; group is the abbreviation for each group label of MA lines; lexA3, the SOS-uninducible strain. Data for the wild-type strain and lexA3 strains are from this study; those of the ΔmutS and the ΔmutY strains are from our previous study (Long et al. 2016)