Table 2.
Mutation rates of the wild-type, lexA3, ΔmutS and ΔmutY MA lines
| Strain | Group | BPSs MR | Confidence intervals | Indels MR | Confidence intervals | ||
|---|---|---|---|---|---|---|---|
| Wild-type | WA | 2.08 | 1.56 | 2.72 | 2.36 | 0.87 | 5.13 |
| 1.06 | 0.29 | 2.72 | 5.31 | 0.64 | 19.2 | ||
| Wild-type | WB | 2.33 | 1.8 | 2.98 | 2.55 | 1.03 | 5.26 |
| 2.22 | 1.01 | 4.21 | 2.46 | 0.06 | 13.7 | ||
| Wild-type | WC | 3.96 | 3.22 | 4.82 | 6.34 | 3.62 | 10.3 |
| 3.47 | 1.85 | 5.93 | 5.34 | 0.65 | 19.3 | ||
| Wild-type | WD | 5.26 | 4.35 | 6.30 | 12.9 | 8.65 | 18.6 |
| 4.80 | 2.74 | 7.79 | 12.0 | 3.27 | 30.7 | ||
| Wild-type | WE | 6.29 | 5.31 | 7.39 | 11.5 | 7.56 | 16.7 |
| 6.28 | 3.94 | 9.51 | 8.56 | 1.77 | 25.0 | ||
| lexA3 | LA | 1.58 | 1.14 | 2.14 | 0.75 | 0.09 | 2.72 |
| 0.762 | 0.157 | 2.23 | 0 | 0 | 9.37 | ||
| lexA3 | LB | 1.91 | 1.44 | 2.48 | 3.75 | 1.87 | 6.71 |
| 1.38 | 0.507 | 3.01 | 2.30 | 0.06 | 12.8 | ||
| lexA3 | LC | 1.96 | 1.47 | 2.56 | 4.43 | 2.29 | 7.74 |
| 1.49 | 0.548 | 3.25 | 2.49 | 0.06 | 13.9 | ||
| lexA3 | LD | 2.92 | 2.23 | 3.76 | 3.90 | 1.68 | 7.67 |
| 1.64 | 0.533 | 3.83 | 0 | 0 | 12.1 | ||
| lexA3 | LE | 4.31 | 3.41 | 5.37 | 6.00 | 2.99 | 10.7 |
| 3.31 | 1.51 | 6.27 | 3.67 | 0.09 | 20.5 | ||
| ΔmutS | SA | 232 | 218 | 247 | 440 | 379 | 509 |
| ΔmutS | SB | 268 | 252 | 284 | 426 | 365 | 494 |
| ΔmutS | SC | 290 | 274 | 308 | 541 | 470 | 620 |
| ΔmutS | SD | 287 | 275 | 299 | 393 | 351 | 438 |
| ΔmutS | SE | 334 | 316 | 353 | 649 | 571 | 735 |
| ΔmutY | YA | 16.9 | 14.8 | 19.2 | 4.34 | 1.59 | 9.45 |
| ΔmutY | YC | 18.1 | 16.2 | 20.3 | 2.87 | 0.93 | 6.70 |
| ΔmutY | YD | 25.4 | 22.9 | 28.1 | 6.75 | 3.24 | 12.4 |
| ΔmutY | YE | 24.5 | 22.1 | 27.2 | 6.02 | 2.75 | 11.4 |
| ΔmutY | YF | 23.2 | 20.8 | 25.9 | 21.1 | 14.3 | 30.2 |
Mutation rates are in units of per nucleotide site per cell division. Bolded areas show information at four-fold degenerate sites. BPSs MR, base-substitution mutation rate (× 10–10); Indels MR, small indels mutation rate (× 10–11); confidence intervals are 95% Poisson confidence intervals (applying to tables below too) for BPSs MR (× 10–10) and Indels MR (× 10–11) respectively; group is the abbreviation for each group label of MA lines; lexA3, the SOS-uninducible strain. Data for the wild-type strain and lexA3 strains are from this study; those of the ΔmutS and the ΔmutY strains are from our previous study (Long et al. 2016)