Table 1.
Demographic, preoperative, operative and postoperative details
| Total no. of patients included | 1348 | |
| Age (years), mean (s.d.) | 66.0 (9.8) | |
| Female gender | 587 (42.4) | |
| BMI (kg/m2), mean (s.d.) | 25.5 (4.4) | Unknown/not recorded: 561 (40.5) |
| Preoperative co-morbidities | ||
| Diabetes | 277 (20.6) | Unknown/not recorded: 38* |
| Cardiovascular | 590 (42.6) | |
| Respiratory | 142 (10.5) | |
| Preoperative biliary stent | 875 (63.3) | Unknown/not recorded: 2* |
| Neoadjuvant chemotherapy received | 61 (4.6) | |
| Preoperative blood tests, median (i.q.r.) | ||
| Bilirubin (µmol/l) | 42 (10-52) | Unknown/not recorded: 2 (0.1) |
| Albumin (g/l) | 10 (32-42) | Unknown/not recorded: 100 (7.4) |
| Neutrophils (×109/l) | 2.8 (3.7-6.5) | Unknown/not recorded: 28 (2.1) |
| Lymphocytes (×109/l) | 1.2 (1.3-2.5) | Unknown/not recorded: 28 (2.1) |
| ASA grade > II | 467 (33.7) | Unknown/not recorded: 116* |
| Positive nodes on preoperative CT | 324 (27.7) | Unknown/not recorded: 177* |
| Type of PD performed | Classic Whipple: 660 (49.1) Pylorus-preserving PD: 685 (50.9) |
Unknown/not recorded: 3* |
| Pancreatic anastomosis | P-J: 1064 (81.2) P-G: 246 (18.8) |
Unknown/not recorded: 38* |
| Concomitant venous resection | 205 (15.5) | Unknown/not recorded: 28* |
| Concomitant arterial resection | 25 (1.9) | Unknown/not recorded: 29* |
| Intraoperative blood transfusion | 164 (18.1) | Unknown/not recorded: 442* |
| Unplanned return to theatre | 74 (5.5) | |
| Length of stay (days), median (i.q.r.) | 10 (10-20) | Unknown/not recorded: 70 (5.2) |
| 30-day unplanned readmission | 134 (10.0) | Unknown/not recorded: 5 (0.4) |
| 90-day mortality | 51 (4.0) | |
| Postoperative histology | ||
| PDAC | 792 (58.8) | |
| AA | 364 (27.0) | |
| CC | 192 (14.2) |
Values are n (%) unless otherwise indicated. AA, ampullary adenocarcinoma; CC, cholangiocarcinoma; CT, computed tomography; HDU, high dependency unit; PD, pancreatoduodenectomy; PDAC, pancreatic ductal adenocarcinoma; P-G, pancreato-gastrostomy; P-J, pancreato-jejunostomy. *Not included in percentages.