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Assessment of TMB status between tissue-based and blood-based assays by disease ontology, for (A) samples with MSAF≥1% and (B) samples with MSAF≥1% to <10% versus ≥10%. Number of sample pairs is shown inside each bar. aData are shown for the top five most frequent disease ontologies among samples with MSAF≥1%. CUP, carcinoma of unknown primary; MSAF, maximum somatic allele frequency; PPA, positive percentage agreement; TMB, tumor mutational burden.
