Table 3.
Inhibitory activity of 6c, 6l, and 6o against DHFR enzyme
| Compd. no. | IC50 (μM) |
|---|---|
| 6c | 3.25 ± 0.15 |
| 6l | 6.30 ± 0.20 |
| 6o | 7.40 ± 0.25 |
| Trimethoprim | 8.40 ± 0.15 |
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