TABLE 3.
Survival Fraction and Radiosensitizing Effect of TRT With or Without Gd-NPs (10 mg/mL) in Different Cell Lines
| Survival fraction (%) | Radiosensitizing effect | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cell line | 1 MBq/mL | 1 MBq/mL + Gd-NPs | Predicted* | 2 MBq/mL | 2 MBq/mL + Gd-NPs | Predicted* | 4 MBq/mL | 4 MBq/mL + Gd-NPs | Predicted* | 1 MBq/mL | 2 MBq/mL | 4 MBq/mL |
| SK-OV-3-luc | 84.4 ± 8.8 | 57.6 ± 9.9 | 70.9 | 67.0 ± 7.5 | 54.3 ± 6.3 | 54.3 | 48.5 ± 12.4 | 40.2 ± 8.9 | 35.9 | 1.46 | 1.23 | 1.20 |
| A-431 | 85.4 ± 7.3 | 64.6 ± 10.7 | 74.8 | 62.3 ± 7.3 | 42.4 ± 8.9 | 54.6 | 43.1 ± 3.8 | 33.5 ± 2.8 | 37.8 | 1.32 | 1.59 | 1.28 |
| OVCAR-3 | 82.3 ± 10.5 | 60.8 ± 10.1 | 72.1 | 60.4 ± 10.1 | 42.8 ± 11.6 | 52.9 | 37.5 ± 10.6 | 30.4 ± 9.9 | 32.9 | 1.35 | 1.41 | 1.23 |
*
Values based on Bliss independence model.