FIGURE 2.

(A) SPECT/CT-derived uptake in HT-1080.hFAP and HT-1080.wt tumors and in organs of 3 mice after injection of 5 MBq of ¹⁷⁷Lu-BioncoFAP at 250 nmol/kg. Supplemental Figure 3 and Supplemental Table 2 compare SPECT/CT-based biodistribution of ¹⁷⁷Lu-BioncoFAP at 250 nmol/kg and ¹⁷⁷Lu-BioncoFAP and ¹⁷⁷Lu-OncoFAP at 3 nmol/kg. (B) Calculated self-absorbed doses for tumors and organs. Supplemental Table 3 provides all dose values and statistical comparisons. *P < 0.05. %ID = percentage injected dose.