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(A) Comparison of [89Zr]GPC1 mAb PET/CT images (clone T2) with and without injection of nonradiolabeled GPC1 mAb (300 μg) before injection of [89Zr]GPC1 mAb clone T2 in PANC-1 xenograft mice (arrows indicate PANC-1 xenografts). (B) Comparison of tumoral uptake on [89Zr]GPC1 mAb PET (clone T2) and biodistribution. (C) Whole-body distribution of [89Zr]GPC1 mAb clone T2 24 h after administration. *P = 0.05 compared with blocking group.
