TABLE 2.
Correlations Between 68Ga-FAPI PET/CT Parameters and Pathologic Response
| Parameter | pCR | Non-pCR | P | Concentric withdrawal | Diffuse withdrawal | P |
|---|---|---|---|---|---|---|
| Primary tumor | ||||||
| SUVmax1 | 18.1 ± 6.4 | 14.9 ± 5.2 | 0.224 | 15.8 ± 6.1 | 16.1 ± 5.3 | 0.92 |
| SUVmax2 | 4.7 ± 2.9 | 12.7 ± 8.4 | 0.024 | 6.3 ± 3.7 | 15.8 ± 9.4 | 0.017 |
| SUVmax3 | 1.1 ± 0.3 | 5.2 ± 3.9 | 0.001 | 2.2 ± 1.8 | 6.4 ± 4.5 | 0.024 |
| ΔSUVmax1 (%) | −70.5 ± 25.6 | −14.6 ± 46.2 | 0.008 | −53.8 ± 31.1 | −1.5 ± 53.0 | 0.008 |
| ΔSUVmax2 (%) | −93.5 ± 2.0 | −64.8 ± 18.8 | 0.001 | −83.1 ± 15.1 | −60.7 ± 20.9 | 0.008 |
| TBR1 | 14.7 ± 3.1 | 15.7 ± 7.9 | 0.662 | 15.4 ± 7.0 | 15.3 ± 7.0 | 0.974 |
| TBR2 | 4.8 ± 4.0 | 11.9 ± 7.4 | 0.027 | 6.3 ± 3.8 | 14.6 ± 8.4 | 0.02 |
| TBR3 | 1.0 ± 0.3 | 4.7 ± 3.6 | 0.001 | 1.9 ± 1.3 | 5.9 ± 4.2 | 0.022 |
| Metastatic lymph node | ||||||
| SUVmax1 | 11.7 ± 8.1 | 10.5 ± 6.2 | 0.723 | 9.2 ± 6.6 | 14.2 ± 6.0 | 0.113 |
| SUVmax2 | 2.1 ± 1.0 | 6.6 ± 7.4 | 0.054 | 2.7 ± 1.9 | 9.3 ± 9.2 | 0.111 |
| SUVmax3 | 0.2 ± 0.6 | 2.2 ± 1.5 | 0.001 | 0.9 ± 1.3 | 2.7 ± 1.4 | 0.014 |
| ΔSUVmax1 (%) | −76.7 ± 10.0 | −41.7 ± 43.6 | 0.053 | −64.0 ± 19.4 | −36.3 ± 58.7 | 0.25 |
| ΔSUVmax2 (%) | −98.8 ± 3.1 | −77.5 ± 13.1 | 0.001 | −88.3 ± 15.1 | −78.7 ± 13.2 | 0.171 |
TBR1 = TBR at baseline.