Description and functions of the significant proteins uniquely identified among those in the up-regulated CM. This information was obtained from the UniProtKB database.

Accession	Protein name	Biological process
Q6P5H2 NEST_MOUSE	Nestin	Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells
Q8VDW0 DX39A_MOUSE	ATP-dependent RNA helicase DDX39A	Involved in pre-mRNA splicing, required for the export of mRNA out of the nucleus
P61161 ARP2_MOUSE	Actin-related protein 2	Regulating gene transcription and repair of damaged DNA, the Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks
Q99PT1 GDIR1_MOUSE	Rho GDP-dissociation inhibitor 1	Controls Rho proteins homeostasis. Regulating their stability and protecting them from degradation
O08784 TCOF_MOUSE	Treacle protein	Nucleolar protein acting as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification