Table 2.
Commercial database analyses for gene expression of select immune cells in tumor-resected GBM from younger and older adult human patients.
| Immune cell | A <65, N = 902 | A ≥65, N = 530 | A P value | B <65, N = 648 | B ≥65, N = 367 | B P value | Significant datasets |
|---|---|---|---|---|---|---|---|
| MQ | 0.010259 | 0.020132 | 0.008 | 0.71 | 0.71 | 0.853 | 1 |
| NK cell | 0.059850 | 0.060562 | 0.576 | 0.12 | 0.11 | 0.838 | 0 |
| CD4+ T cell | 0.00 | 0.00 | 0.939 | 0.05 | 0.06 | 0.700 | 0 |
| CD8+ T cell | 0.00 | 0.00 | 0.454 | 0.000 | 0.000 | 0.850 | 0 |
| B cell | 0.064778 | 0.064242 | 0.249 | 0.06 | 0.06 | 0.969 | 0 |
Data from Caris Life Sciences (Database A) and Tempus (Database B) for gene expression of common immunologic markers as stratified by <65 or ≥65 years of age. Significance, or lack thereof, for each data point across both datasets is included in the final column.