Table 2.

Overview of N-protein species compared in biophysical experiments

designation	N-protein mutations	n exclusive instances(1)	occur in # of distinct sequences(2)	occurs in % of all genomes(3)	in set of defining VOC mutations(4)
N:R203K/G204R	R203K, G204R	53,282	17,552	57%	α, γ, ο
N:P13L/Δ31–33	P13L, Δ31–33	9,548	12,503	47%	ο
Nο	P13L, Δ31–33, R203K, G204R	791,613	10,238	46%	ο (all BA.1)(5)
Nδ	D63G, R203M, G215C, D377Y	> 1.2×106	9,397	33%	δ (all 21J)(5)
N:G215C	G215C	60	10,562	34%	δ
N:D63G	D63G	182	12,443	36%	δ
Nref	none	38,929	NA	3.6%	NA

⁽¹⁾Number of genomes where the indicated mutations are the only N mutations.

⁽²⁾Number of unique N-protein sequences in which indicated mutations are present, alongside other mutations.

⁽³⁾Percentage of all sequenced genomes carrying the specific mutation.

⁽⁴⁾Variants of concern for which indicated mutations are part (or all) of the defining set of N-mutations.

⁽⁵⁾These sets of mutations comprise all defining N-protein mutations of this variant.

⁽⁵⁾Literature on definition or biophysical characterization of the mutant.