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[Preprint]. 2023 Nov 21:2023.11.20.567960. [Version 1] doi: 10.1101/2023.11.20.567960

Table 1. Summary of survival cassette designs used in K562 armoring tests.

Schematic description of gene-coding sequences inserted between lentiviral packaging elements of host transfer plasmid. All cassettes were placed under a constitutive MNDU3 promoter.

Name Cassette configuration
Survival1 BCL2-P2A-XIAP-T2A-MCL1
Survival2 XIAP-P2A-BCL2-IRES(VCIP)-tCD34-T2A-MCL1
Survival3 XIAP-P2A-BCL2-IRES(ECMV)-tCD34-T2A-MCL1