Table 1.
Type I hair cell KV activation voltage dependence and kinetics. Mean ± SEM (number of cells). g is effect size, Hedge’s g. KWA is Kruskal-Wallis ANOVA.
| Zone | Kv1.8 | Tail V1/2, mVa | Tail S, mVb | Tail Gmax, nSc | Tail Gmax/Cm, nS/pFd | Age (median, range) |
|---|---|---|---|---|---|---|
| Extrastriola | +/+ | −85 ± 2 (12) | 4.3 ± 0.4 (12) | 270 ± 40 (11) | 47 ± 8 (11) | 22, 14–287 |
| +/− | −83 ± 1 (40) | 5.2 ± 0.3 (40) | 210 ± 20 (40) | 37 ± 4 (40) | 19, 13–259 | |
| −/− | −40.2 ± 0.9 (26) | 5.7 ± 0.3 (26) | 5.4 ± 0.3 (26) | 1.11 ± 0.08 (26) | 45, 14–277 | |
| Striola | +/+ | −87 ± 3 (6) | 4.3 ± 0.3 (6) | 310 ± 70 (6) | 41 ± 7 (6) | 40, 15–59 |
| +/− | −88 ± 2 (3) | 4.7 ± 0.9 (3) | 270 ± 60 (3) | 44 ± 6 (3) | 19, 14–20 | |
| −/− | −38 ± 1 (13) | 6.2 ± 0.4 (13) | 6.5 ± 0.6 (13) | 1.5 ± 0.1 (13) | 202, 14–370 |
a
−/− vs +/+: 2-way ANOVA, p < 1E-9, g 7.7; −/− vs +/−: 2-way ANOVA, p < 1E-9, g 6.8
b
−/− vs +/+: 2-way ANOVA, p = 8.4E-4, g 1.2
c
−/− vs +/+: 2-way ANOVA, p < 1E-9, g 3.7; −/− vs +/−: 2-way ANOVA, p < 1E-9, g 2.1
d
−/− vs +/+: 2-way ANOVA, p < 1E-9, g 3.6; −/− vs +/−: 2-way ANOVA, p < 1E-9, g 2.0