Table 5.
Type II hair cell passive membrane properties. Mean ± SEM (number of cells). g is effect size, Hedge’s g. KWA is Kruskal-Wallis ANOVA.
| Zone | Kv1.8 | Vrest, mV | Rinput, GΩa | τrc, msb | Peak height, mV, 170c | Peak time, msd | Cm, pF | Age (median, range) |
|---|---|---|---|---|---|---|---|---|
| Extrastriola | +/+ | −71 ± 2 (19) | 1.4 ± 0.2 (16) | 11 ± 3 (16) | −20 ± 2 (15) | 2.5 ± 0.2 (15) | 4.7 ± 0.2 (50) | 45, 16–312 |
| +/− | −71 ± 2 (34) | 1.2 ± 0.1 (27) | 9 ± 1 (27) | −20 ± 1 (30) | 2.44 ± 0.08 (30) | 4.6 ± 0.1 (52) | 27, 13–280 | |
| −/− | −76 ± 2 (9) | 2.3 ± 0.3 (7) | 16 ± 3 (7) | 2 ± 6 (7) | 3.6 ± 0.3 (7) | 4.6 ± 0.2 (35) | 53, 15–154 | |
| Striola | +/+ | −73.1 ± 1.0 (6) | 1.4 ± 0.1 (6) | 9 ± 1 (6) | −20 ± 2 (5) | 2.7 ± 0.1 (5) | 4.6 ± 0.2 (7) | 45, 40–224 |
| +/− | −71 ± 3 (5) | 1.4 ± 0.3 (6) | 7 ± 2 (6) | −20 ± 2 (6) | 2.3 ± 0.1 (6) | 4.8 ± 0.2 (6) | 19, 19–30 | |
| −/− | −68 ± 2 (6) | 3.0 ± 0.7 (6) | 26 ± 10 (6) | 2 ± 7 (4) | 4 ± 1 (4) | 4.4 ± 0.3 (7) | 178, 29–298 |
a
−/− vs +/+: KWA, p = 0.015, g 1.2; −/− vs +/−: KWA, p = 0.002, g 1.5
b
−/− vs +/+: KWA, p = 0.016, g 0.7; −/− vs +/−: KWA, p = 0.008, g 1.2
c
−/− vs +/+: KWA, p = 0.006, g 2.1; −/− vs +/−: KWA, p = 2E-4, g 2.6
d
−/− vs +/+: 2-way ANOVA, p <1E-9, g 1.3; −/− vs +/−: 2-way ANOVA, p < 1E-9, g 1.9