Figure 2: Much of the transcriptome changes with age.

(A) Pearson correlation coefficient of all genes vs the two archetypes. Genes with high positive $R^2$ are strongly monotonically increasing whereas genes with high negative $R^2$ are monotonically decreasing. Genes selected as archetype centers are to the left and right of the purple lines. (b) Rescaled expression data for genes with correlation coefficients ≥ 0.9 (top) and ≤ −0.9 (bottom).