Table 1.
Summary statistics, p-values, and Spearman correlation coefficients to assess whether sex, age, or BMI are associated with neutrophil bioenergetics or S. aureus phagocytosis. Subject demographics are shown across the top of the columns.Significant differences between males and females were tested with a two tailed t-test for parametric data and a Wilcoxon signed-rank test for nonparametric data. Significant p-values are bolded.
| BIOENERGETICS | ||||||||
|---|---|---|---|---|---|---|---|---|
| Metric | Total (N = 29) | Male (N = 15) | Female (N = 14) | Sex | Age (28 ± 7 yrs, range 19–46) | BMI (25 ± 4, range 18.3–34.4) | ||
| Value | Mean ± SD | Mean ± SD | Mean ± SD | P-value | Correlation | P-value | Correlation | P-value |
| OCR Maximum (pmol/min) | 1120 ± 249 | 1121 ± 249 | 1120 ± 258 | 0.9962 | −30.13 | 0.4857 | 0.10 | 0.6144 |
| OCR AUC (total pmol) | 68110 ± 16109 | 66785 ± 14325 | 69530 ± 18268 | 0.6579 | −0.15 | 0.4348 | −0.07 | 0.7124 |
| OCR Time to Maximum (minutes) | 56 ± 5 | 57 ± 6 | 56 ± 5 | 0.8613 | −0.10 | 0.5925 | −0.02 | 0.9059 |
| OCR Time to Baseline (minutes) | 227 ± 10 | 225 ± 14 | 230 ± 1 | 0.2196 | −0.14 | 0.4610 | 0.01 | 0.9756 |
| ECAR Maximum (mpH/min) | 71 ± 11 | 72 ± 13 | 70 ± 10 | 0.6517 | −0.11 | 0.5661 | −0.05 | 0.7799 |
| ECAR AUC (total mpH) | 4859 ± 818 | 4964 ± 923 | 4746 ± 706 | 0.4797 | −0.20 | 0.2887 | −0.22 | 0.2436 |
| ECAR Time to Maximum (minutes) | 52 ± 6 | 52 ± 6 | 51 ± 6 | 0.6783 | −0.03 | 0.8862 | −0.11 | 0.5761 |
| ECAR Time to Baseline (minutes) | 230 ± 1 | 230 ± 1 | 230 ± 1 | 0.4559 | −0.20 | 0.2968 | −0.06 | 0.7573 |
| PHAGOCYTOSIS | ||||||||
| Metric | Total (N = 20) | Male (N = 10) | Female (N = 10) | Sex | Age (29 ± 10 yrs, range 20–62) | BMI (24 ± 5, range 18.7–38.4) | ||
| Value | Mean ± SD | Mean ± SD | Mean ± SD | P-value | Correlation | P-value | Correlation | P-value |
| Phagocytosis (MFI) | 26087 ± 17324 | 34007 ± 17053 | 18167 ± 14262 | 0.0374 | −0.12 | 0.6217 | 0.20 | 0.3995 |