Table 5.
Details of instrument output discrepancies with statistical significance.
| Biomarker | Instruments | Mean 1 (pg/mL) | Mean 2 (pg/mL) | Δ (pg/mL) | % Difference* | 95% CI (pg/mL) | P-value, adjusted† |
|---|---|---|---|---|---|---|---|
| ApoE | 200 vs FM3D | 819.5 | 796.1 | 22.4 | 2.8% | 4.6 to 40.1 | 0.0107 |
| MMP-9 | MPX vs 200 | 166.7 | 175.1 | −8.4 | 5.0% | −14.0 to −2.9 | 0.0020 |
| MPX vs FM3D | 166.7 | 174.1 | −7.4 | 4.4% | −14.0 to −0.8 | 0.0261 | |
| SDC1 | MPX vs 200 | 13986.0 | 13690.0 | 295.3 | 2.2% | 91.9 to 498.8 | 0.0031 |
| 200 vs FM3D | 13690.0 | 13991.0 | −301.1 | 2.2% | −494.2 to −108.1 | 0.0015 |
*
Differences calculated as the absolute value of the A divided by the lower of the two mean protein values x 100, with % differences rounded to nearest 0.1%.
†
P-values calculated by repeated measures ANOVA with Tukey post-test correction for multiple comparisons. All concentration values rounded to nearest 0.1 picogram.
Instrument Abbreviations: 200 = Luminex 200; FM3D = FlexMap 3D; MPX = MagPix.