Figure 2. Transaortic constriction (TAC)-induced heart failure decreases body weight and muscle mass.
Wild-type C57BL/6J mice were subjected to sham and TAC surgeries for 14 weeks. (A) Body weight, (B) gastrocnemius (gastroc.) muscle weight, (C) soleus muscle weight, (D) tibialis anterior muscle weight, (E) extensor digitorum longus (EDL) muscle weight. Muscle weights were normalized to tibia length. Data are shown as the mean ± SEM, n=10 mice in each group,*p<0.02 vs sham-operated mice.