Table 3. . Pre-index period Duchenne muscular dystrophy-related healthcare resource utilization procedures and events in matched eteplirsen-treated and control patients.

	Pre-index period
	Eteplirsen-treated (n = 389)	Control (n = 389)	t-test
Length of pre-index period in months, mean (SD)	10.57 (1.76)	10.63 (1.67)	–
Hospital encounters
Yearly average care-adjusted number, mean (SD)	3.70 (7.75)	3.73 (7.77)	0.954
Yearly average days, mean (SD)	1.97 (4.12)	1.82 (3.47)	0.581
Emergency room
Yearly average care-adjusted number, mean (SD)	0.71 (2.20)	0.65 (2.02)	0.681
Yearly average days, mean (SD)	0.42 (1.09)	0.39 (1.15)	0.741
Intensive care unit
Yearly average care-adjusted number, mean (SD)	0.13 (1.13)	0.05 (0.51)	0.179
Yearly average days, mean (SD)	0.12 (1.05)	0.05 (0.43)	0.176
Pulmonary management
Yearly average number, mean (SD)	0.96 (3.46)	0.85 (3.85)	0.661
Motorized wheelchair
Yearly average number, mean (SD)	0.82 (2.30)	0.77 (2.19)	0.775
Ever have motorized wheelchair, n (%)	94 (24.16)	97 (24.94)	0.803
Scoliosis
Yearly average number, mean (SD)	0.92 (6.04)	0.53 (1.89)	0.217
Cardiac management
Yearly average number, mean (SD)	1.49 (2.93)	1.40 (2.70)	0.646
Tracheostomy
Yearly average number, mean (SD)	0.98 (11.07)	0.80 (7.24)	0.785
Cough assist device
Yearly average number, mean (SD)	0.41 (1.73)	0.45 (1.93)	0.759
Ever have cough assist device, n (%)	58 (14.91)	54 (13.88)	0.683
Assisted ventilation
Yearly average number, mean (SD)	0.99 (6.78)	0.76 (6.41)	0.630

SD: Standard deviation.