Table 6. . Scenario analyses.
| Scenario | ICER (Cost/QALY) for Pegcetacoplan vs | |
|---|---|---|
| Eculizumab | Ravulizumab | |
| Mean weight (63.72 kg) | Dominant | $94,568 |
| Incremental number of transfusions per cycle equal to 0 | Dominant | Dominant |
| Time horizon | ||
| 5 years | Dominant | Dominant |
| 10 years | Dominant | Dominant |
| 25 years | Dominant | Dominant |
| End point definition | ||
| Hemoglobin normalization – proportion estimated with Weibull distribution | Dominant | Dominant |
ICER: Incremental cost–effectiveness ratio, QALY: Quality-adjusted life year.