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. 2023 Aug 22;12(9):e220175. doi: 10.57264/cer-2022-0175

Table 3. . Sensitivity analysis results for costs per patient over a 15-year time horizon for all first-line and second-line treatments without treatment switching or delay.

Treatment Non-disease modifying therapy costs
  Absolute cost Incremental cost of ofatumumab vs comparator
First-line therapies
  Ofatumumab $177,808
  Ocrelizumab $182,956 $5148
  Teriflunomide $222,578 $44,770
  Dimethyl fumarate $207,828 $30,020
  Glatiramer acetate $219,234 $41,427
  Avonex $219,945 $42,137
  Rebif 44 $221,279 $43,471
  Betaseron $219,907 $42,099
  Extavia $219,907 $42,099
  BSC $246,279 $68,471
Second-line therapies
  Cladribine $195,163 $17,355
  Natalizumab $182,289 $4482
  Fingolimod $204,538 $26,730

Results for administration and monitoring costs are not presented for the 15-year analysis as they do not change from the 10-year results.

BSC: Best supportive care.