Extended Data Fig. 6 |. Increase of HLA-E surface expression on monocyte-derived macrophages and enhanced Jurkat^NKG2A activity against these cells after IFN-γ treatment.

Monocytes were isolated from nine healthy donors and differentiated to monocyte-derived macrophages that were exposed to IFN-γ overnight (both unpulsed and VL9^G-pulsed). Peptide pulsing was performed at 37°C for one hour prior to co-culture with reporter cells. P values for comparison between IFN-γ-treated and untreated cells were determined by a two-sided paired t-test.