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. 2003 Jul;1(3):189–200. doi: 10.3121/cmr.1.3.189

Table 2.

Cost comparison of combination agents versus component agents separately.

Agent Maximum effective dose (mg) Cost/year ($)a Pills/day Component cost/year ($)a Pills/day
Glucovance* 2.5/500, 2 bid 1,400 4 730 3
Avandamet* 2/500, 2 bid 2,170 4 2,550 4
Metaglip* 5/500, 2 bid 1,400 4 775 4

aAverage wholesale price for brand name and maximal allowable cost for generic preparations.

*Glucophage-XR, Glucovance and Metaglip (Bristol-Myers Squibb Company, Princeton, NJ); Avandamet (GlaxoSmithKline, Research Triangle Park, NC).