Table 5.

Advantages and disadvantages of pharmacologic treatments for smoking cessation.

Treatment	Advantages	Disadvantages
Patch and/or gum	Available over the counter	Not approved by FDA; avoid use with dentures; temporomandibular joint disorder; adhesive allergies
Nicotine nasal spray	Higher, quicker nicotine levels	Unpleasant adverse events initially; avoid use with chronic nasal allergies
Nicotine inhaler	Mimics hand-to-mouth behavior	Low nicotine levels
Bupropion hydrochloride	Non-nicotine; can be used in combination with patch; decreased weight gain; mood stabilization with nicotine withdrawal	Must screen for seizures

From reference 59.