Table 3.
Discrimination ability for each score to predict invasive mechanical ventilation applied in the database of COVID-19 patients (complete case analysis) and comparison of the ABC2-SPH and other existing scores.
| Scores | Number patients | Number IMV patients | AUROC (95% CI) | Brier score | p-value1,2 |
|---|---|---|---|---|---|
| ABC2-SPH (5) | 6,849 | 1,442 (21.0) | 0.694 (0.679–0.710) | 0.351 | - |
| CALL (17) | 537 | 107 (19.9) | 0.664 (0.609–0.720) | 0.314 | 0.246 |
| COVID-IRS (18) | 439 | 90 (20.5) | 0.719 (0.659–0.78) | 0.394 | 0.436 |
| CURB-65 (20) | 6,642 | 1,401 (21.0) | 0.615 (0.599–0.631) | 0.320 | <0.001* |
| PREDI-CO (20) | 261 | 41 (15.7) | 0.648 (0.561–0.736) | 0.367 | 0.660 |
| SOFA (21) | 2,639 | 587 (22.2) | 0.682 (0.658–0.707) | 0.248 | 0.040 |
| STSS (22) | 6,858 | 1,378 (20.0) | 0.642 (0.626–0.658) | 0.440 | <0.001* |
| SUM (23) | 7,883 | 1,635 (20.7) | 0.662 (0.647–0.677) | 0.382 | <0.001* |
| 4C Mortality Score (24) | 779 | 175 (22.4) | 0.672 (0.628–0.716) | 0.388 | 0.598 |
1p-value of the comparison between ABC2-SPH and each score. 2Due to the multiple comparisons, alpha was corrected using Bonferroni method, to 0.00625. *ABC2-SPH has higher discrimination ability. AUROC: area under the receiving operator characteristic curve. The main information for each score is shown in Supplementary Table S1. The bold values are to highlight that they are statistically significant.