Table 5.
Discrimination ability for each score to predict invasive mechanical ventilation applied in the database of COVID-19 patients <80 years-old admitted to hospital with COVID-19, from January 1, 2021, to March 31, 2022 (complete case analysis).
| Score* | Number of patients | Number of IMV patients | AUROC (95% CI) | Brier | p-value |
|---|---|---|---|---|---|
| Before recalibration | |||||
| ABC2-SPH (5) | 5,553 | 1,160 | 0.714 (0.698–0.731) | 0.312 | - |
| SUM (23) | 6,369 | 1,305 | 0.668 (0.652–0.685) | 0.373 | <0.001 |
| STSS (22) | 5,604 | 1,121 | 0.650 (0.633–0.667) | 0.410 | <0.001 |
| CURB65 (22) | 5,383 | 1,114 | 0.623 (0.605–0.641) | 0.288 | <0.001 |
| SOFA (21) | 2,152 | 474 | 0.702 (0.676–0.729) | 0.240 | 0.006 |
1p-value of the comparison between ABC2-SPH and each score. 2Due to the multiple comparisons, alpha was corrected using Bonferroni method, to 0.0125. AUROC, area under the receiving operator characteristic curve. The main information for each score is shown in Supplementary Table S1. *It was not possible to test CALL, COVID-IRS, PREDI-CO and 4C Mortality Score, as the number of patients and events was lower than recommended by the TRIPOD checklist (14, 15). The bold values are to highlight that they are statistically significant.