Table 3.

Evaluation of the clinical efficacy of the PFO closure procedure in adolescents with migraine.

	M0	M6	M12
VAS	7.63 ± 0.87	2.56 ± 2.85	2.12 ± 2.65
HIT-6	66.94 ± 4.80	46.28 ± 12.25	43.99 ± 10.85
PedMIDAS	49.73 ± 7.52	12.40 ± 15.63	8.60 ± 15.38
Frequency	7.35 ± 2.60	2.23 ± 2.90	1.60 ± 2.72
Duration	12.34 ± 3.44	4.05 ± 4.88	3.27 ± 4.73
Migraine burden	91.87 ± 44.62	20.73 ± 34.13	15.48 ± 34.42

VAS, Visual Analogue Scale; HIT-6, Headache Impact Test; PedMIDSA, Pediatric Migraine Disability Assessment; M0, Baseline; M6, at 6 months postoperatively; M12, at 12 months postoperatively; PFO, patent foramen ovale.