Table 3.
Multivariate analysis of PREPARE score components as risk factors for major morbidity.
Variables | Category | Hazard ratio | 95% CI | P |
---|---|---|---|---|
Albumin level (g/dl) | <3.5 vs. ≥3.5 | 1.454 | 0.101–21.017 | 0,784 |
Elective surgery | No/Yes | NA | NA | |
Type of surgical procedure | PD/PPPD vs. DP/TP | 3.849 | 1.208–12.264 | 0.023 |
Pathology of pancreatic origin | No/Yes | 2.200 | 0.817–5.928 | 0.119 |
Heart rate (bpm) | <50 or >80 vs. 50–80 | 2.875 | 0.962–8.596 | 0.059 |
Systolic blood pressure (mmHg) | <110 or >130 vs. 110–130 | 0.930 | 0.367–2.358 | 0.879 |
Hemoglobin level (g/dl) | <11.5 or >17 vs. 11.5–17 | 0.194 | 0.023–1.622 | 0.130 |
ASA score | III/IV vs. I/II | 3.089 | 1.067–8.947 | 0.038 |
Differences in major morbidity were analyzed using a multivariable Cox-regression model. ASA, American society of anesthesiologists; CI, confidence interval; DP, distal pancreatectomy; PD, pancreaticoduodenectomy; PPPD, pylorus-preserving pancreaticoduodenectomy; TP, total pancreatectomy.
Bold values are statistical significance.