Figure 2.

Receiver-operating-characteristic (ROC) curves for various cut-off levels of plasma C-reactive protein (CRP), procalcitonin (PCT) and sTREM-1 in differentiating between presence and absence of infection. Areas under the ROC curves: 0.97 for sTREM-1, 0.85 for PCT, and 0.77 for CRP. At a cut-off of 60 ng/ml, sTREM-1 correctly classifies patients as suffering from infection with 96% sensitivity and 89% specificity. (Reprinted with permission. Gibot et al. Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis. Ann Int Med 2004;141:9–15. Copyright 2004 American College of Physicians. All rights reserved.)