Table 2.
Comparative analysis of the different variables according to the responses to therapy of 674 patients with DTC.
| Variables | Excellent response (n = 461) | Indeterminate (n = 65) | Biochemical incomplete (n = 83) | Structural incomplete (n = 65) | p-values |
|---|---|---|---|---|---|
| Gender | |||||
| Men Women |
9 (2.0%) 452 (98.0%) |
21 (32.3%) 44 (67.7%) |
20 (24.1%) 63 (75.9%) |
53 (81.5%) 12 (18.5%) |
0.019* |
| With obesity | |||||
| Yes No |
216 (46.9%) 245 (53.1%) |
29 (44.6%) 36 (55.4%) |
33 (39.8%) 50 (60.2%) |
44 (67.7%) 21 (32.3%) |
0.025* |
| Pathologic diagnosis | |||||
| Papillary Follicular |
428 (92.8%) 33 (7.2%) |
53 (81.5%) 12 (18.5%) |
68 (81.9%) 15 (18.1%) |
60 (92.3%) 5 (7.7%) |
0.003* |
| Age in years, mean ± SD | 47.7 ± 11.9 | 45.8 ± 16.9 | 46.7 ± 14.6 | 46.2 ± 13.8 | 0.621 |
| BMI at last visit in kg/cm2, mean ± SD | 29.2 ± 6.2 | 29.9 ± 7.5 | 28.8 ± 6.3 | 31.5 ± 7.1 | 0.038 |
| Duration of follow-up in years, mean ± SD | 6.9 ± 4.7 | 3.6 ± 3.9 | 5.0 ± 4.1 | 5.2 ± 4.5 | <0.001 |
| Preoperative findings | |||||
| Lymphovascular invasion, n (%) | 23 (5.0%) | 42 (64.6%) | 41 (49.4%) | 32 (49.2%) | 0.006 |
| Surgical margins, n (%) | 60 (13.0%) | 11 (16.9%) | 16 (19.3%) | 11 (16.9%) | 0.399* |
| Extranodal involvement, n (%) | 2 (0.4%) | 5 (7.7%) | 12 (14.5%) | 11 (16.9%) | <0.001* |
| Extrathyroidal extension, n (%) | 12 (2.6%) | 60 (92.3%) | 15 (18.1%) | 25 (38.5%) | 0.176* |
| Number of positive LN, mean ± SD | 1.01 ± 0.8 | 1.01 ± 0.8 | 1.22 ± 0.8 | 1.02 ± 0.8 | 0.536 |
| Size of cancer in cm, mean ± SD | 1.9 ± 1.6 | 2.3 ± 1.8 | 2.5 ± 2.6 | 2.6 ± 2.3 | 0.003 |
| Size of the largest LN in cm, mean ± SD | 1.2 ± 0.8 | 1.5 ± 1.4 | 1.6 ± 1.2 | 1.8 ± 1.3 | 0.286 |
*Comparative analysis of the different variables according to the responses to therapy done using the chi-square test for categorical variables. Mean and SD comparison between the different responses to therapy was done using the one-way analysis of variance (ANOVA).