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. 2023 Nov 17;10:1289321. doi: 10.3389/fmed.2023.1289321

Table 1.

The review of prophylaxis of post-extubation stridor.

Intervention Dose Route of administration n Primary author Age Type of surgery and technique Anesthetic details Time range Type of research Hospital and country
Supine/ prone / / 242 Xiang (3) NA ERCP NA NA A randomized controlled trial NA
Supine/ lateral / / 92 Jung (4) 3–12 yr NA NA NA A randomized clinical trial Yungpook National University; Korea
Albuterol spray 2 puffs inhaled 120 Maddah (5) 52.34 ±8.95 yr NA NA In 2021 A bouble-blind randomized clinical trial 5 Azar Educational Hospital in Gorgan; Northern Iran
Dexamethasone 8 mg TID first 24 h; 4 mg BID next 24 h iv 110 Amoozadeh (2) 52.1 ± 14.1 yr Neck surgery NA April 2021 to July 2021 An observational prospective cohort study Imam Khomeini Hospital's; Iran
Remifentanil/ ambroxol hydrochloride/ budesonide suspension Remifentanil/ 0.5 μg/g; ambroxol 15 mg hydrochloride; budesonide suspension 0.5 mg iv/ inhaled 46 Yang (6) NA Removing the tonsil under general anesthesia and adenoidectomy under nasal endoscope NA NA A randomized clinical trial Cangzhou Central Hospital; China
Tracheal tubes / / 2246 Weiss (7) 1.93 (1.48) yr in the cuffed and 1.87 (1.45) yr in the uncuffed ENT, Head surgery, Cleft, Thoracic, Abdominal, Laparoscopy, Urology, Limb, Cardiac catheterization, Gastroenter, Radiology, and Others NA NA A prospective, randomized, controlled multi-center trial University Children's Hospital Zurich; 24 European pediatric anesthesia centers; Switzerland
Bloodletting acupuncture / / 60 Saghaei (8) 33.8 (18.6); 38.37 (15.5) (month) Scheduled for elective surgery Atropine 10 μg.kg−1; Midazolam 25–100 μg.kg−1; thiopental 5 mg.kg−1; Fentanyl 1 μg.kg−1; Succinylcholine 2 mg.kg−1; halothane NA A double-blind, randomized trial NA
Cuffed vs. uncuffed endotracheal intubation / / 40 Nishat (9) 3–10 yr Oral surgeries, Sevoflurane February to December 2019 A randomized controlled study NA
Lidocaine topical 4 mg/kg of 2%; intravenous 1 mg/kg of 2% iv / 134 Koç (10) 7.1 ± 1.7; 6.7 ± 1.3 yr; 7.6 ± 2.4 yr; 6.3 ± 0.8 yr Tonsillectomy and/or adenoidectomy Atropine, 0.015 mg/kg, meperidine, 1 mg/kg; gas mixture of N2O, O2, and halothane NA A randomized controlled trial NA
Dexmedetomidine Dexmedetomidine 2.0 μg/kg im 100 Ambesh (11) 35.64 ± 14.93 yr; 38.08 ± 12.58 yr Laminectomy for PIVD Midazolam (0.05 mg/kg); Propofol (1.5–2.0 mg/kg); fentanyl (2.0 μg/kg); Vecuronium bromide (0.12 mg/kg), mixture of 50% air in oxygen and isoflurane (1%). September 2014 to September 2016 A double blind placebo controlled study Departm NA Anesthesiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences; Lucknow
Sealing cuff pressure / / 60 Al-Metwalli (12) 8.35 ± 1.63 yr; 8.45 ± 1.76 yr; 8.2 ± 1.54 yr Dental surgery N2O free general anesthesia; 0.2 mg/kg oral diazepam; fentanyl 2 μg/kg and propofol 2.5 mg/kg. NA A prospective controlled, randomized, blinded study. NA
Flexible laryngeal mask / / 90 Naguib (13) 3.24 ± 0.857 yr; 3.13 ± 0.815 yr NA Atropine 0.01 mg/kg; Fentanyl 1 μg/kg; Sevoflurane 3.5% in oxygen to air of 1:1 July 2018 to April 2019. A randomized trial Department of Pediatric Surgery, Tanta University Hospitals; Egypt