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. 2023 Nov 17;14:1309835. doi: 10.3389/fimmu.2023.1309835

Table 1.

Basic characteristics of participates with RA based on NLR category.

Characteristic Overall (n=2002) Higher NLR (n=339) Lower NLR (n=1663) P value
Weighted No. 44,689,857 7,531,516 37,158,342
Age (year) 56.61 (14.43) 62.19 (14.72) 55.48 (14.11) <0.001
Age group <0.001
 20-39 years 161 (11.56%) 20 (6.63%) 141 (12.56%)
 40-59 years 641 (41.06%) 73 (27.58%) 568 (43.79%)
 60-79 years 941 (35.99%) 174 (47.13%) 767 (33.73%)
 ≥80 years 259 (11.39%) 72 (18.66%) 187 (9.91%)
Sex 0.11
 Female 1,173 (58.74%) 170 (53.05%) 1,003 (59.89%)
 Male 829 (41.26%) 169 (46.95%) 660 (40.11%)
Race/ethnicity <0.001
 Mexican American 324 (5.89%) 49 (6.09%) 275 (5.85%)
 Other Hispanic 154 (4.85%) 25 (4.68%) 129 (4.88%)
 Non-Hispanic White 878 (68.93%) 192 (75.66%) 686 (67.57%)
 Non-Hispanic Black 569 (15.98%) 54 (7.48%) 515 (17.70%)
 Other/multiracial 77 (4.35%) 19 (6.09%) 58 (3.99%)
Educational attainment 0.7
 Less than 9th grade 349 (9.56%) 54 (9.98%) 295 (9.47%)
 9-11th grade 406 (17.41%) 61 (16.18%) 345 (17.66%)
 High school graduate 482 (28.10%) 91 (29.89%) 391 (27.74%)
 Some college 544 (31.21%) 92 (32.93%) 452 (30.86%)
 College graduate or above 221 (13.72%) 41 (11.02%) 180 (14.27%)
Poverty income ratio 2.52 (1.58) 2.36 (1.51) 2.55 (1.60) 0.2
Poverty income ratio group 0.061
 0-1.29 807 (31.03%) 128 (32.49%) 679 (30.73%)
 1.30-3.49 749 (37.62%) 140 (42.79%) 609 (36.57%)
 ≥3.50 446 (31.35%) 71 (24.72%) 375 (32.70%)
BMI (kg/m2) 30.31 (7.37) 29.79 (7.38) 30.41 (7.37) 0.2
BMI group 0.3
 Underweight 23 (1.24%) 4 (2.35%) 19 (1.01%)
 Normal 423 (22.80%) 90 (26.19%) 333 (22.12%)
 Overweight 613 (29.71%) 99 (29.71%) 514 (29.71%)
 Obese 943 (46.25%) 146 (41.75%) 797 (47.16%)
Waist circumference (cm) 103.03 (16.96) 103.52 (17.49) 102.93 (16.85) >0.9
Smoking status 0.3
 Non-smoker 868 (40.04%) 148 (36.76%) 720 (40.71%)
 Smoker 1,134 (59.96%) 191 (63.24%) 943 (59.29%)
Health insurance 0.7
 Insured 1,751 (87.99%) 302 (87.23%) 1,449 (88.14%)
 Uninsured 251 (12.01%) 37 (12.77%) 214 (11.86%)
NLR 2.38 (1.41) 4.66 (1.89) 1.91 (0.63) <0.001

Continuous variables are expressed as mean ± standard deviation (SD), while categorical variables are presented as number (%). All estimates were adjusted for sample weights and complex survey designs, with means and percentages further adjusted for the survey weights of NHANES. RA, rheumatoid arthritis; BMI, body mass index; NLR, neutrophil to lymphocyte ratio.