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. 2023 Nov 30;23:897. doi: 10.1186/s12888-023-05377-5

Table 1.

Endorsement of specific symptoms of DSM criteria for major depression, melancholia, and atypical specifiers in patients with MDD, MDD with melancholia features, and MDD with atypical features, as determined by the AUDADIS-IV

AUDADIS-MDE AUDADIS-Mel AUDADIS-Aty
Symptom % (n) % (n) % (n)
Sad mood 94.97 5460 95.51 2277 94.12 769
Anhedonia 87.60 5036 100 2384 85.68 700
Appetite/weight decreasea 60.08 3454 86.45 2061 17.87 146
Appetite/weight increaseb 36.42 2094 29.07 693 100 817
Insomnia sleep onset 69.42 3991 84.02 2003 46.88 383
Early morning awakening 54.90 3156 82.38 1964 21.67 177
Hypersomniab 46.83 2692 40.86 974 100 817
Psychomotor retardationa 40.76 2343 61.37 1463 30.23 247
Psychomotor agitationa 37.50 2156 60.74 1448 20.20 165
Fatigue 84.71 4870 84.94 2025 92.66 757
Worthlessness 62.55 3596 74.20 1769 59.73 488
Guilta 58.13 3342 81.92 1953 47.49 388
Diminished concentration 84.71 4870 91.99 2193 80.78 660
Indecisiveness 75.77 4356 85.19 2031 71.60 585
Suicidal ideation/Thoughts of dying 59.51 3421 65.18 1554 56.55 462
Suicide attempt 11.05 635 14.60 348 8.94 73

a also a symptom of the ‘melancholic features’ specifier,

b also a symptom of the ‘atypical features’ specifier