Table 2.
Descending Aortic Biomechanics Before and After Interventions
| SAVR (n = 40) | TAVR (n = 40) | |||||
|---|---|---|---|---|---|---|
| Pre | Post | p | Pre | Post | p | |
| Global circumferential strain, GCS [%] | 4.4 [3.3,5.3] | 4.7 [3.9,5.6] | 0.32 | 10.7 [4.5,14.6] | 17.0 [6.1,20.9] | 0.009 |
| Pulse pressure corrected strain [%/mm Hg] (GCS/PP) | 6.8 [5.5,9.2] | 7.6 [6.1,10.8] | 0.20 | 13.6 [8.6,23.5] | 26.8 [10.6,32.0] | 0.012 |
| Time to peak strain, TTP [ms] | 300 [270,334] | 195 [167,250] | < 0.001 | 315 [285,400] | 300 [280,385] | 0.33 |
| Δ Αrea/TTP [cm2/s] | 1.3 [0.9,1.9] | 2.5 [1.8,3.1] | < 0.001 | 2.2 [1.5,3.7] | 2.6 [1.8,4.2] | 0.22 |
| Distensibility [10–3 mmHg−1] | 1.5 [1.1,2.0] | 1.4 [1.1,1.7] | 0.52 | 3.6 [1.9,6.7] | 4.9 [1.4,7.6] | 0.76 |
| Δ Αrea [cm2] | 0.4 [0.3,0.6] | 0.5 [0.4,0.6] | 0.11 | 0.9 [0.4,1.2] | 0.7 [0.6,1.4] | 0.53 |
| Fractional area change [%] | 9.4 [6.8,11.9] | 10.5 [9.3,13.5] | 0.09 | 30.0 [9.1,40.8] | 32.9 [103,57.1] | 0.22 |
| End systolic area [cm2] | 5.3 [4.1,5.9] | 4.8 [4.1,6.0] | 0.81 | 4.6 [3.7,5.6] | 4.4 [3.3,5.7] | 0.90 |
| End diastolic area [cm2] | 4.8 [3.7,5.7] | 4.3 [3.6,5.4] | 0.65 | 3.3 [2.6,4.9] | 3.3 [2.5,4.7] | 0.76 |
cm centimeters, GCS Global circumferential strain [%], ms milliseconds, PP pulse pressure, SAVR surgical aortic valve replacement, TAVR transcatheter aortic valve replacement, TTP, time to peak