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. 2023 Dec 1;24:275. doi: 10.1186/s13059-023-03112-7

Table 2.

Benchmark results for correcting reads from real datasets. Indels/100 kbp: average number of insertion or deletion errors per 100,000 aligned bases. Mismatches/100 kbp = average number of mismatch errors per 100,000 aligned bases. Genome fraction (GF) reflects how much of each of the strain-specific genomes is covered by the corrected reads. N/100 kbp denotes the average number of uncalled bases (Ns) per 100,000 bases in the read. MC = fraction of misassembled contigs

Correction Indels/100 kbp Mismatches/100 kbp GF (%) N/100 kbp MC (%)
Correct Bmock12 ONT reads
     ONT reads 4001.58 2659.11 93.63 0.00 2.33
     Ratatosk 31.17 94.91 93.74 0.67 2.64
     R-HERO 6.45 40.48 93.78 0.20 2.57
     FMLRC 8.09 21.82 93.77 0.00 2.93
     F-HERO 5.87 20.82 93.77 0.06 2.92
     LoRDEC 8.10 22.56 93.76 0.00 2.73
     L-HERO 5.03 20.54 93.81 0.06 2.70
Correct Bmock12 PacBio reads
     PacBio reads 7790.78 1851.43 87.98 0.00 7.55
     Ratatosk 335.23 152.21 91.76 1.16 10.53
     R-HERO 59.87 58.89 92.31 0.25 12.28
     FMLRC 30.39 46.53 94.84 0.00 18.14
     F-HERO 20.76 42.45 94.88 0.03 18.55
     LoRDEC 40.99 60.44 93.00 0.00 15.32
     L-HERO 18.95 53.01 93.51 0.04 17.09
Correct NWC ONT reads
     ONT reads 7991.02 5476.30 100.00 0.00 7.18
     Ratatosk 433.92 589.11 99.99 22.42 7.22
     R-HERO 198.49 426.52 100.00 13.25 7.49
     FMLRC 225.39 340.97 99.99 0.00 10.35
     F-HERO 97.17 270.36 99.99 0.00 10.70
     LoRDEC 154.4 489.82 99.99 0.00 7.18
     L-HERO 72.05 377.92 99.99 0.00 9.65
Correct NWC PacBio reads
     PacBio reads 11479.15 5270.85 81.61 0.00 7.54
     Ratatosk 369.40 446.14 83.13 13.65 6.12
     R-HERO 190.04 301.22 83.45 8.66 5.58
     FMLRC 244.74 239.31 84.62 0.00 5.14
     F-HERO 108.63 171.05 84.49 0.00 5.01
     LoRDEC 79.42 422.12 83.19 0.00 5.01
     L-HERO 54.68 373.06 83.00 0.00 4.76

Boldface is meant to indicate the best performing tool in the respective category