Table 6.

Delivered dose (DD, mg)/Emitted dose (ED, mg) for adult breathing patterns. The DD/ED (%) values of the five nebulizers for the asthma adult breathing pattern decreased compared to those for the normal adult breathing pattern at all IgG concentrations

Breathing pattern	IgG conc. (mg/mL)	JN-PARIr (%)	JN-PARIb (%)	SMN-U150 (%)	VMN-SM1 (%)	VMN-SM3 (%)
ISO 27427	1	40.48 ± 3.11*	35.15 ± 4.38	25.27 ± 1.12*	29.72 ± 1.78	15.17 ± 0.55
	10	40.51 ± 1.74*	37.33 ± 3.22*	26.00 ± 0.60*	31.35 ± 1.63	16.55 ± 0.66*
	20	41.23 ± 0.44*	38.32 ± 1.15*	28.23 ± 1.61*	33.33 ± 0.50*	21.30 ± 0.04*
	40	31.14 ± 1.53*	32.32 ± 3.22*	26.62 ± 1.26*	31.46 ± 2.81	18.02 ± 1.43*
Normal adult	1	34.50 ± 2.10	34.44 ± 1.56	21.71 ± 0.79	31.54 ± 1.09	17.17 ± 3.35
	10	34.43 ± 0.76	29.24 ± 0.78	19.72 ± 0.95	29.13 ± 0.89	14.29 ± 0.73
	20	29.13 ± 0.95	26.78 ± 0.97	20.03 ± 0.81	24.82 ± 0.28	16.34 ± 0.44
	40	35.37 ± 1.63	23.91 ± 0.40	20.48 ± 1.14	28.03 ± 0.28	15.56 ± 0.57
Asthma adult	1	26.91 ± 2.27*	25.63 ± 0.30	17.76 ± 2.19*	26.16 ± 1.35*	13.42 ± 0.40
	10	21.70 ± 0.32*	20.66 ± 0.80*	14.91 ± 0.89*	17.28 ± 0.27*	10.26 ± 0.36*
	20	23.36 ± 2.32*	22.71 ± 1.78*	14.83 ± 0.33*	21.09± 0.37*	12.44 ± 0.28*
	40	22.59 ± 1.29*	19.26 ± 0.85*	15.40 ± 0.63*	19.20 ± 0.37*	10.51 ± 0.21*

All data are presented as mean ± SD values. * p < 0.05, versus the normal adult pattern