Table 7.

Delivered dose (DD, mg) for child breathing patterns. The DD values of the five nebulizers for the child asthma breathing pattern decreased compared to those for the normal child breathing pattern at all IgG concentrations

Breathing pattern	IgG conc. (mg/mL)	JN-PARIr (mg)	JN-PARIb (mg)	SMN-U150 (mg)	VMN-SM1 (mg)	VMN-SM3 (mg)
Normal child	1	0.280 ± 0.01	0.197 ± 0.02	0.256 ± 0.00	0.422 ± 0.00	0.253 ± 0.01
	10	2.353 ± 0.13	1.591 ± 0.08	1.937 ± 0.11	2.695 ± 0.21	1.700 ± 0.14
	20	5.199 ± 0.37	4.260 ± 0.44	4.724 ± 0.40	5.856 ± 0.09	3.648 ± 0.13
	40	8.787 ± 0.21	6.101 ± 0.54	7.194 ± 0.33	11.013 ± 0.78	5.864 ± 0.69
Asthma child	1	0.212 ± 0.01*	0.135 ± 0.00*	0.190 ± 0.02*	0.297 ± 0.01*	0.216 ± 0.01*
	10	2.017 ± 0.07*	1.419 ± 0.14	1.572 ± 0.06*	2.457 ± 0.20	1.256 ± 0.16*
	20	3.584 ± 0.10*	2.495 ± 0.18*	3.045 ± 0.14*	4.105 ± 0.13*	2.352 ± 0.08*
	40	7.118 ± 0.32*	5.234 ± 0.15	6.012 ± 0.08*	7.883 ± 0.11*	4.939 ± 0.24

All data are presented as the mean ± SD values. * p < 0.05, versus the normal child pattern