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. 2023 Nov 30;22:209. doi: 10.1186/s12944-023-01945-6

Table 2.

The associations of the quartile of serum carotenoids, relative to Quartile 1 with VAI

Categories Range Model1 Model2 Model3
β (95%CI) β (95%CI) β (95%CI)
α-carotene (ug/dL)
Continuous −0.29 (− 0.36, − 0.21) −0.31 (− 0.39, − 0.23) −0.25 (− 0.33, − 0.16)
Q1 < 1.40 ref ref ref
Q2 1.40–2.70 −0.47 (− 0.82, − 0.12) −0.52 (− 0.88, − 0.16) −0.49 (− 0.83, − 0.14)
Q3 2.70–5.00 −0.64 (− 0.95, − 0.33) −0.73 (− 1.05, − 0.40) −0.70 (− 1.04, − 0.36)
Q4 ≥ 5.00 −0.93 (− 1.24, − 0.63) −1.05 (− 1.38, − 0.72) −0.98 (− 1.34, − 0.62)
P for trend < 0.001 < 0.001 < 0.001
β-carotene (ug/dL)
Continuous −0.35 (− 0.47, − 0.24) −0.41 (− 0.54, − 0.27) −0.32 (− 0.44, − 0.20)
Q1 < 7.50 ref ref ref
Q2 7.50–12.89 −0.59 (− 0.93, − 0.26) −0.65 (− 0.99, − 0.30) −0.62 (− 0.97, − 0.26)
Q3 12.89–23.30 −0.73 (− 1.01, − 0.46) −0.86 (− 1.15, − 0.57) −0.85 (− 1.17, − 0.54)
Q4 > 23.30 −1.28 (− 1.60, − 0.96) −1.52 (− 1.87, − 1.17) −1.39 (− 1.77, − 1.00)
P for trend < 0.001 < 0.001 < 0.001
β-cryptoxanthin (ug/dL)
Continuous −0.26 (− 0.38, − 0.14) −0.27 (− 0.39, − 0.14) −0.28 (− 0.42, − 0.14)
Q1 < 4.80 ref ref ref
Q2 4.80–7.70 −0.42 (− 0.77, − 0.08) −0.41 (− 0.75, − 0.07) −0.42 (− 0.76, − 0.09)
Q3 7.70–12.70 −0.60 (− 0.89, − 0.32) −0.60 (− 0.88, − 0.32) −0.57 (− 0.90, − 0.24)
Q4 > 12.70 −0.76 (− 1.08, − 0.43) −0.78 (− 1.10, − 0.45) −0.79 (− 1.18, − 0.41)
P for trend < 0.001 < 0.001 < 0.001
Lutein/zeaxanthin (ug/dL)
Continuous −0.18 (− 0.28, − 0.08) −0.23 (− 0.32, − 0.13) −0.28 (− 0.39, − 0.16)
Q1 < 10.46 ref ref ref
Q2 10.46–14.50 −0.09 (− 0.41, 0.22) −0.12 (− 0.43, 0.19) −0.19 (− 0.46, 0.09)
Q3 14.50–20.10 −0.42 (− 0.62, − 0.21) −0.47 (− 0.68, − 0.27) −0.54 (− 0.79, − 0.29)
Q4 ≥ 20.10 −0.40 (− 0.64, − 0.16) −0.51 (− 0.75, − 0.27) −0.68 (− 0.96, − 0.39)
P for trend < 0.001 < 0.001 < 0.001
Trans-lycopene (ug/dL)
Continuous −0.12 (− 0.24, 0.00) −0.08 (− 0.21, 0.04) −0.33 (− 0.53, − 0.12)
Q1 < 14.00 ref ref ref
Q2 14.00–20.11 −0.48 (− 0.85, − 0.09) −0.39 (− 0.78, 0.00) −0.38 (− 0.81, 0.04)
Q3 20.11–28.23 −0.39 (− 0.79, 0.00) −0.28 (− 0.70, 0.14) −0.46 (− 0.96, 0.04)
Q4 ≥ 28.23 −0.48 (− 0.87, − 0.10) −0.38 (− 0.78, 0.02) −0.88 (− 1.50, − 0.27)
P for trend 0.023 0.104 0.005

Model 1: no cofounder; Model 2: adjusted for age, sex; Model 3: further adjusted for race, education level, marital status, alcohol intake, smoking status, leisure-time physical activity, BMI, the family of poverty ratio, TC, hypertension, diabetes, and CVD.