Table 3.
TACE intervention timing (n = 35) | |
1st line therapy failure | 19 (54.3%) |
2nd line therapy failure | 10 (28.5%) |
3rd line therapy failure | 5 (14.3%) |
4th line therapy failure | 1 (2.9%) |
No. of liver metastasis (n = 35) | |
1 | 6 (17.1%) |
2 | 2 (5.7%) |
4 | 1 (2.9%) |
≧5 | 26 (74.3%) |
Location of liver metastasis (n = 35) | |
Right lobe | 10 (28.6%) |
Left lobe | 0 (0%) |
Both lobes | 25 (71.4%) |
Tumor burden of liver (n = 35) | |
10 ~ 30% | 19 (54.3%) |
30 ~ 50% | 10 (28.6%) |
50 ~ 70% | 6 (17.1%) |
Number of DEB-TACE courses (n = 35) | |
1 | 19 (54.3%) |
2 | 8 (22.8%) |
3 | 4 (11.4%) |
4 | 1 (2.9%) |
5 | 3 (8.6%) |
Median | 1 |
Total embolization numbers | 66 |
DEB-TACE agent (n = 66) | |
Irinotecan | 60 (90.9%) |
Epirubicin | 6 (9.1%) |
Best response (n = 35) | |
Partial response (PR) | 5 (14.3%) |
Stable disease (SD) | 14 (40.0%) |
Progressive disease (PD) | 13 (37.1%) |
Not availablea | 3 (8.6%) |
Disease control rate (PR + SD) | 19 (54.3%) |
aOne patient died 2 months later after the first DEB-TACE due to intra-abdominal infection and gastrointestinal bleeding. Two patient lost follow-up after the first DEB-TACE