Table 4.
Hit compounds in five remarkably enriched pathways
| Pathway | Total | Hit | P value | Impact | Hit compound |
|---|---|---|---|---|---|
| Beta-Alanine metabolism | 21 | 4 | 0.00283 | 0.0560 |
3-Hydroxypropionic acid; 5,6-Dihydrouracil; Uracil; L-Histidine |
|
Histidine metabolism |
16 | 3 | 0.0105 | 0.2213 |
L-Glutamate; L-Histidine; Imidazole-4-acetate |
| D-Glutamine and D-glutamate metabolism | 6 | 2 | 0.0120 | 0.5000 |
L-Glutamate; D-Glutamine |
| Primary bile acid biosynthesis | 46 | 4 | 0.0446 | 0.0259 |
Cholic acid; Glycochenodeoxycholate; Glycocholate; Taurocholate |
| Steroid hormone biosynthesis | 85 | 5 | 0.1030 | 0.2615 |
17-alpha-Hydroxyprogesterone; Testosterone; Androstenedione; Androsterone; 16-Glucuronide-estriol |