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. 2023 Nov 30;54:114. doi: 10.1186/s13567-023-01245-y

Figure 10.

Figure 10

SC inhibits PRRSV infection by regulating the TRAF2/NF-κB signalling pathway. PRRSV infection promotes activation of the NF-κB signalling pathway via inhibition of TRAF2 expression, thus promoting self-replication. SC suppresses activation of the NF-κB signalling pathway by promoting the expression of TRAF2, thereby inhibiting PRRSV replication and the expression of inflammatory cytokines. The schematic was drawn using the Biorender website.