Table 3.
All features (excluding position-specific phylogenetic features) | SIFT onlya | Position-specific phylogenetic features only | All features | |||||
---|---|---|---|---|---|---|---|---|
Disease | Neutral | Disease | Neutral | Disease | Neutral | Disease | Neutral | |
Correct classification | 221 | 167 | 257 | 173 | 247 | 217 | 249 | 219 |
Wrong classification | 62 | 77 | 26 | 71 | 36 | 27 | 34 | 25 |
Total number of errors | 139 (26.38%) | 97 (18.41%) | 63 (11.95%) | 59 (11.20%) |
Here, phylogenetic features refer to SIFT score, normalized site entropy and change in residue frequency.
aThe classification obtained by logistic regression analysis using only the SIFT score as the determining feature.