Table 5.
The results of logistic regression analysis of variations in TM regions
| All features excluding position-specific phylogenetic features | SIFT only | Position-specific phylogenetic features only | All features | |||||
|---|---|---|---|---|---|---|---|---|
| Disease | Neutral | Disease | Neutral | Disease | Neutral | Disease | Neutral | |
| Correct classification | 143 | 58 | 157 | 68 | 155 | 71 | 155 | 80 |
| Wrong classification | 21 | 31 | 7 | 21 | 9 | 18 | 9 | 9 |
| Total number of errors | 52 (20.55%) | 28 (11.07%) | 27 (10.67%) | 18 (7.11%) | ||||
Here, phylogenetic features refer to SIFT score, normalized site entropy and change in residue frequency.